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miR‐132 loss de‐represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain

microRNA‐132 (miR‐132) is involved in prosurvival, anti‐inflammatory and memory‐promoting functions in the nervous system and has been found consistently downregulated in Alzheimer's disease (AD). Whether and how miR‐132 deficiency impacts AD pathology remains, however, unaddressed. We show her...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Salta, Evgenia, Sierksma, Annerieke, Vanden Eynden, Elke, De Strooper, Bart
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009807/
https://ncbi.nlm.nih.gov/pubmed/27485122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606520
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