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A Pipeline for Reconstructing Somatic Copy Number Alternation’s Subclonal Population-Based Next-Generation Sequencing Data

State-of-the-art next-generation sequencing (NGS)-based subclonal reconstruction methods perform poorly on somatic copy number alternations (SCNAs), due to not only it needs to simultaneously estimate the subclonal population frequency and the absolute copy number for each SCNA, but also there exist...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Chu, Yanshuo, Nie, Chenxi, Wang, Yadong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058119/
https://ncbi.nlm.nih.gov/pubmed/32180789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01374
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