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CCL5-armed oncolytic virus augments CCR5-engineered NK cell infiltration and antitumor efficiency

BACKGROUND: Natural killer (NK) cells have potent antitumor activities. Nevertheless, adoptive transfer therapy of NK cells has gained very limited success in patients with solid tumors as most infused NK cells remain circulating in the peripheral blood instead of entering tumor sites. Chemokines an...

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Dades bibliogràfiques
Publicat a:J Immunother Cancer
Autors principals: Li, Feng, Sheng, Yuqiao, Hou, Weizhou, Sampath, Padma, Byrd, Daniel, Thorne, Stephen, Zhang, Yi
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057442/
https://ncbi.nlm.nih.gov/pubmed/32098828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2019-000131
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