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CCL5, CCR1 and CCR5 in murine glioblastoma: immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5

Glioblastoma multiforme (GBM) is the most malignant brain tumor. Microglia/macrophages are found within human GBM where they likely promote tumor progression. We report that CCL5, CCR1, and CCR5 are expressed in glioblastoma. Individual deletion of CCR1 or CCR5 had little to no effect on survival of...

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Detalhes bibliográficos
Main Authors: Pham, Kien, Luo, Defang, Liu, Che, Harrison, Jeffrey K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335967/
https://ncbi.nlm.nih.gov/pubmed/22425022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2012.02.009
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