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Functional Tolerance to Cysteine Mutations in Human α7 Nicotinic Acetylcholine Receptors

The α7 nicotinic acetylcholine receptor (α7 nAChR) is involved in various intracellular signaling pathways that mediate addiction, chronic pain, and other diseases, but its intracellular domain structures remain undetermined. The presence of seventeen native cysteines in α7 nAChR provides opportunit...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Tillman, Tommy S., Choi, Zachary, Xu, Yan, Tang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057392/
https://ncbi.nlm.nih.gov/pubmed/31951367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00647
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