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Extending the scope of coiled-coil crystal structure solution by AMPLE through improved ab initio modelling

The phase problem remains a major barrier to overcome in protein structure solution by X-ray crystallography. In recent years, new molecular-replacement approaches using ab initio models and ideal secondary-structure components have greatly contributed to the solution of novel structures in the abse...

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Publicat a:Acta Crystallogr D Struct Biol
Autors principals: Thomas, Jens M. H., Keegan, Ronan M., Rigden, Daniel J., Davies, Owen R.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057219/
https://ncbi.nlm.nih.gov/pubmed/32133991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798320000443
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