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Ab initio solution of macromolecular crystal structures without direct methods

The majority of macromolecular crystal structures are determined using the method of molecular replacement, in which known related structures are rotated and translated to provide an initial atomic model for the new structure. A theoretical understanding of the signal-to-noise ratio in likelihood-ba...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: McCoy, Airlie J., Oeffner, Robert D., Wrobel, Antoni G., Ojala, Juha R. M., Tryggvason, Karl, Lohkamp, Bernhard, Read, Randy J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389281/
https://ncbi.nlm.nih.gov/pubmed/28325875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701640114
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