Systems Genetics of Optic Nerve Axon Necrosis During Glaucoma

In this study, we identify genomic regions that modulate the number of necrotic axons in optic nerves of a family of mice, some of which have severe glaucoma, and define a set of high priority positional candidate genes that modulate retinal ganglion cell (RGC) axonal degeneration. A large cohort of...

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Bibliographic Details
Published in:Front Genet
Main Authors: Stiemke, Andrew B., Sah, Eric, Simpson, Raven N., Lu, Lu, Williams, Robert W., Jablonski, Monica M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056908/
https://ncbi.nlm.nih.gov/pubmed/32174956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00031
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