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Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma

Within the white matter, axonal loss by neurodegeneration is coupled to glial cell changes in gene expression, structure and function commonly termed gliosis. Recently, we described the highly variable expansion of gliosis in degenerative optic nerves from the DBA/2J mouse model of chronic, age-rela...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Eye Res
Hauptverfasser: Bosco, Alejandra, Breen, Kevin T., Anderson, Sarah R., Steele, Michael R., Calkins, David J., Vetter, Monica L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972706/
https://ncbi.nlm.nih.gov/pubmed/26851485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.01.014
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