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Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma

Within the white matter, axonal loss by neurodegeneration is coupled to glial cell changes in gene expression, structure and function commonly termed gliosis. Recently, we described the highly variable expansion of gliosis in degenerative optic nerves from the DBA/2J mouse model of chronic, age-rela...

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Bosco, Alejandra, Breen, Kevin T., Anderson, Sarah R., Steele, Michael R., Calkins, David J., Vetter, Monica L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972706/
https://ncbi.nlm.nih.gov/pubmed/26851485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.01.014
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