Loss of Fractalkine Signaling Exacerbates Axon Transport Dysfunction in a Chronic Model of Glaucoma

Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from neurons to myeloid cells. Signaling through its rece...

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Bibliografske podrobnosti
izdano v:Front Neurosci
Main Authors: Breen, Kevin T., Anderson, Sarah R., Steele, Michael R., Calkins, David J., Bosco, Alejandra, Vetter, Monica L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Neuroscience
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123443/
https://ncbi.nlm.nih.gov/pubmed/27932942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00526
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