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Norrin protects optic nerve axons from degeneration in a mouse model of glaucoma

Norrin is a secreted signaling molecule activating the Wnt/β-catenin pathway. Since Norrin protects retinal neurons from experimental acute injury, we were interested to learn if Norrin attenuates chronic damage of retinal ganglion cells (RGC) and their axons in a mouse model of glaucoma. Transgenic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Leopold, Stephanie A., Zeilbeck, Ludwig F., Weber, Gregor, Seitz, Roswitha, Bösl, Michael R., Jägle, Herbert, Fuchshofer, Rudolf, Tamm, Ernst R., Ohlmann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660254/
https://ncbi.nlm.nih.gov/pubmed/29079753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14423-8
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