Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila

Mitochondrial alternative NADH dehydrogenase (aNDH) was found to extend lifespan when expressed in the fruit fly. We have found that fruit flies expressing aNDH from Ciona intestinalis (NDX) had 17–71% lifespan prolongation on media with different protein-tocarbohydrate ratios except NDX-expressing...

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Detalhes bibliográficos
Publicado no:Biogerontology
Main Authors: Gospodaryov, Dmytro V., Strilbytska, Olha M., Semaniuk, Uliana V., Perkhulyn, Natalia V., Rovenko, Bohdana M., Yurkevych, Ihor S., Barata, Ana G., Dick, Tobias P., Lushchak, Oleh V., Jacobs, Howard T.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056681/
https://ncbi.nlm.nih.gov/pubmed/31749111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-019-09849-8
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