Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila

Mitochondrial alternative NADH dehydrogenase (aNDH) was found to extend lifespan when expressed in the fruit fly. We have found that fruit flies expressing aNDH from Ciona intestinalis (NDX) had 17–71% lifespan prolongation on media with different protein-tocarbohydrate ratios except NDX-expressing...

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Vydáno v:Biogerontology
Hlavní autoři: Gospodaryov, Dmytro V., Strilbytska, Olha M., Semaniuk, Uliana V., Perkhulyn, Natalia V., Rovenko, Bohdana M., Yurkevych, Ihor S., Barata, Ana G., Dick, Tobias P., Lushchak, Oleh V., Jacobs, Howard T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056681/
https://ncbi.nlm.nih.gov/pubmed/31749111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10522-019-09849-8
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