Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in <i>Drosophila</i>

The insulin&#8722;IGF-1 signaling (IIS) pathway is conserved throughout multicellular organisms and regulates many traits, including aging, reproduction, feeding, metabolism, stress resistance, and growth. Here, we present evidence of a survival-sustaining role for IIS in a subset of gut cells i...

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Bibliographic Details
Main Authors: Olha M. Strilbytska, Uliana V. Semaniuk, Kenneth B. Storey, Ihor S. Yurkevych, Oleh Lushchak
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
insulin signaling pathway
midgut
isc
progenitor cells
lifespan
metabolism
fruit fly
Online Access:https://www.mdpi.com/2073-4409/9/4/803
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