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High-throughput prediction of MHC class I and class II neoantigens with MHCnuggets

Computational prediction of binding between neoantigen peptides and major histocompatibility complex (MHC) proteins can be used to predict patient response to cancer immunotherapy. Current neoantigen predictors focus on in silico estimation of MHC binding affinity and are limited by low predictive v...

詳細記述

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書誌詳細
出版年:Cancer Immunol Res
主要な著者: Shao, Xiaoshan M., Bhattacharya, Rohit, Huang, Justin, Sivakumar, I.K. Ashok, Tokheim, Collin, Zheng, Lily, Hirsch, Dylan, Kaminow, Benjamin, Omdahl, Ashton, Bonsack, Maria, Riemer, Angelika B., Velculescu, Victor E., Anagnostou, Valsamo, Pagel, Kymberleigh A., Karchin, Rachel
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056596/
https://ncbi.nlm.nih.gov/pubmed/31871119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0464
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