High-throughput prediction of MHC class I and class II neoantigens with MHCnuggets

Computational prediction of binding between neoantigen peptides and major histocompatibility complex (MHC) proteins can be used to predict patient response to cancer immunotherapy. Current neoantigen predictors focus on in silico estimation of MHC binding affinity and are limited by low predictive v...

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Udgivet i:Cancer Immunol Res
Main Authors: Shao, Xiaoshan M., Bhattacharya, Rohit, Huang, Justin, Sivakumar, I.K. Ashok, Tokheim, Collin, Zheng, Lily, Hirsch, Dylan, Kaminow, Benjamin, Omdahl, Ashton, Bonsack, Maria, Riemer, Angelika B., Velculescu, Victor E., Anagnostou, Valsamo, Pagel, Kymberleigh A., Karchin, Rachel
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056596/
https://ncbi.nlm.nih.gov/pubmed/31871119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0464
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