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Radiation Induced Oxidation of [(18)F]Fluorothia Fatty Acids Under cGMP Manufacturing Conditions
OBJECTIVE: The objectives of the present work were to optimize and validate the synthesis and stability of 14(R,S)-[(18)F]fluoro-6-thia-heptadecanoic acid ([(18)F]FTHA) and 16-[(18)F]fluoro-4-thia-palmitic acid ([(18)F]FTP) under cGMP conditions for clinical applications. METHODS: Benzyl-14-(R,S)-to...
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| Pubblicato in: | Nucl Med Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7056516/ https://ncbi.nlm.nih.gov/pubmed/31759313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2019.11.004 |
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