Identification of a novel base J binding protein complex involved in RNA polymerase II transcription termination in trypanosomes

Base J, β-D-glucosyl-hydroxymethyluracil, is a modification of thymine DNA base involved in RNA Polymerase (Pol) II transcription termination in kinetoplastid protozoa. Little is understood regarding how specific thymine residues are targeted for J-modification or the mechanism of J regulated transc...

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Gepubliceerd in:PLoS Genet
Hoofdauteurs: Kieft, Rudo, Zhang, Yang, Marand, Alexandre P., Moran, Jose Dagoberto, Bridger, Robert, Wells, Lance, Schmitz, Robert J., Sabatini, Robert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055916/
https://ncbi.nlm.nih.gov/pubmed/32084124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008390
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