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Histone H3 Variant Regulates RNA Polymerase II Transcription Termination and Dual Strand Transcription of siRNA Loci in Trypanosoma brucei

Base J, β-D-glucosyl-hydroxymethyluracil, is a chromatin modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. In Trypanosoma brucei, J is enriched, along with histone H3 variant (H3.V), at sites involved in RNA Polymerase (RNAP) II termination and telomeric...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Reynolds, David, Hofmeister, Brigitte T., Cliffe, Laura, Alabady, Magdy, Siegel, T. Nicolai, Schmitz, Robert J., Sabatini, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721609/
https://ncbi.nlm.nih.gov/pubmed/26796527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005758
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