PINK1‐Dependent Mitophagy Regulates the Migration and Homing of Multiple Myeloma Cells via the MOB1B‐Mediated Hippo‐YAP/TAZ Pathway

The roles of mitochondrial dysfunction in carcinogenesis remain largely unknown. The effects of PTEN‐induced putative kinase 1 (PINK1)‐dependent mitophagy on the pathogenesis of multiple myeloma (MM) are determined. The levels of the PINK1‐dependent mitophagy markers PINK1 and parkin RBR E3 ubiquiti...

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Dades bibliogràfiques
Publicat a:Adv Sci (Weinh)
Autors principals: Fan, Shengjun, Price, Trevor, Huang, Wei, Plue, Michelle, Warren, Jonathan, Sundaramoorthy, Pasupathi, Paul, Barry, Feinberg, Daniel, MacIver, Nancie, Chao, Nelson, Sipkins, Dorothy, Kang, Yubin
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Full Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055555/
https://ncbi.nlm.nih.gov/pubmed/32154065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201900860
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