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Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway

New findings on neural regulation of immunity are allowing the design of novel pharmacological strategies to control inflammation and nociception. Herein, we report that choline, a 7-nicotinic acetylcholine receptor (α7nAChRs) agonist, prevents carrageenan-induced hyperalgesia without affecting infl...

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Detalhes bibliográficos
Publicado no:Brain Res
Main Authors: Kusuda, Ricardo, Carreira, Eleonora Uchôa, Ulloa, Luis, Cunha, Fernando Queiroz, Kanashiro, Alexandre, Cunha, Thiago Mattar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054728/
https://ncbi.nlm.nih.gov/pubmed/31783002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146567
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