High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery

Diabetic nephropathy (DN) is an increasing threat to human health and is regarded as an important public issue. The pathophysiologic mechanisms of DN are complicated. The initiating molecular events triggering the loss function in mesangial cells (MCs) in DN are not well known. In this cross-discipl...

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Bibliografiske detaljer
Udgivet i:Mol Ther
Main Authors: Tsai, Yi-Chun, Kuo, Mei-Chuan, Hung, Wei-Wen, Wu, Ling-Yu, Wu, Ping-Hsun, Chang, Wei-An, Kuo, Po-Lin, Hsu, Ya-Ling
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054723/
https://ncbi.nlm.nih.gov/pubmed/31991106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.01.014
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