Hypoxic Lung-Cancer-Derived Extracellular Vesicle MicroRNA-103a Increases the Oncogenic Effects of Macrophages by Targeting PTEN

Hypoxia, the most commonly observed characteristic in cancers, is implicated in the establishment of an immunosuppressive niche. Recent studies have indicated that extracellular vesicle (EV)-mediated cancer-stroma interactions are considered to play a critical role in the regulation of various cellu...

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Pubblicato in:Mol Ther
Autori principali: Hsu, Ya-Ling, Hung, Jen-Yu, Chang, Wei-An, Jian, Shu-Fang, Lin, Yi-Shiuan, Pan, Yi-Chung, Wu, Cheng-Ying, Kuo, Po-Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835028/
https://ncbi.nlm.nih.gov/pubmed/29292163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.11.016
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