High Glucose Induces Mesangial Cell Apoptosis through miR-15b-5p and Promotes Diabetic Nephropathy by Extracellular Vesicle Delivery

Diabetic nephropathy (DN) is an increasing threat to human health and is regarded as an important public issue. The pathophysiologic mechanisms of DN are complicated. The initiating molecular events triggering the loss function in mesangial cells (MCs) in DN are not well known. In this cross-discipl...

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Bibliografski detalji
Izdano u:Mol Ther
Glavni autori: Tsai, Yi-Chun, Kuo, Mei-Chuan, Hung, Wei-Wen, Wu, Ling-Yu, Wu, Ping-Hsun, Chang, Wei-An, Kuo, Po-Lin, Hsu, Ya-Ling
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2020
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054723/
https://ncbi.nlm.nih.gov/pubmed/31991106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.01.014
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