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Enhanced Loading of Functional miRNA Cargo via pH Gradient Modification of Extracellular Vesicles
Based on their identification as physiological nucleic acid carriers in humans and other organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles for DNA, RNA, and other cargo. However, efficient loading and functional delivery of nucleic acids remain a challenge,...
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| Publicado en: | Mol Ther |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054713/ https://ncbi.nlm.nih.gov/pubmed/31911034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.12.007 |
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