Enhanced Loading of Functional miRNA Cargo via pH Gradient Modification of Extracellular Vesicles

Based on their identification as physiological nucleic acid carriers in humans and other organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles for DNA, RNA, and other cargo. However, efficient loading and functional delivery of nucleic acids remain a challenge,...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Ther
Autores principales: Jeyaram, Anjana, Lamichhane, Tek N., Wang, Sheng, Zou, Lin, Dahal, Eshan, Kronstadt, Stephanie M., Levy, Daniel, Parajuli, Babita, Knudsen, Daphne R., Chao, Wei, Jay, Steven M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054713/
https://ncbi.nlm.nih.gov/pubmed/31911034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.12.007
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares