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Enhanced Loading of Functional miRNA Cargo via pH Gradient Modification of Extracellular Vesicles

Based on their identification as physiological nucleic acid carriers in humans and other organisms, extracellular vesicles (EVs) have been explored as therapeutic delivery vehicles for DNA, RNA, and other cargo. However, efficient loading and functional delivery of nucleic acids remain a challenge,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Mol Ther
Main Authors: Jeyaram, Anjana, Lamichhane, Tek N., Wang, Sheng, Zou, Lin, Dahal, Eshan, Kronstadt, Stephanie M., Levy, Daniel, Parajuli, Babita, Knudsen, Daphne R., Chao, Wei, Jay, Steven M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Gene & Cell Therapy 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054713/
https://ncbi.nlm.nih.gov/pubmed/31911034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.12.007
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