Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial

BACKGROUND: More than a million Americans harbor a cerebral cavernous angioma (CA), and those who suffer a prior symptomatic hemorrhage have an exceptionally high rebleeding risk. Preclinical studies show that atorvastatin blunts CA lesion development and hemorrhage through inhibiting RhoA kinase (R...

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Xehetasun bibliografikoak
Argitaratua izan da:Neurosurgery
Egile Nagusiak: Polster, Sean P, Stadnik, Agnieszka, Akers, Amy L, Cao, Ying, Christoforidis, Gregory A, Fam, Maged D, Flemming, Kelly D, Girard, Romuald, Hobson, Nicholas, Koenig, James I, Koskimäki, Janne, Lane, Karen, Liao, James K, Lee, Cornelia, Lyne, Seán B, McBee, Nichol, Morrison, Leslie, Piedad, Kristina, Shenkar, Robert, Sorrentino, Matthew, Thompson, Richard E, Whitehead, Kevin J, Zeineddine, Hussein A, Hanley, Daniel F, Awad, Issam A
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
Research—Human—Study Protocols
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054711/
https://ncbi.nlm.nih.gov/pubmed/30476251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyy539
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