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IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons

Signalling endosomes are essential for trafficking of activated ligand–receptor complexes and their distal signalling, ultimately leading to neuronal survival. Although deficits in signalling endosome transport have been linked to neurodegeneration, our understanding of the mechanisms controlling th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Fellows, Alexander D, Rhymes, Elena R, Gibbs, Katherine L, Greensmith, Linda, Schiavo, Giampietro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054680/
https://ncbi.nlm.nih.gov/pubmed/32030864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949129
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