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IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons

Signalling endosomes are essential for trafficking of activated ligand–receptor complexes and their distal signalling, ultimately leading to neuronal survival. Although deficits in signalling endosome transport have been linked to neurodegeneration, our understanding of the mechanisms controlling th...

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Podrobná bibliografie
Vydáno v:EMBO Rep
Hlavní autoři: Fellows, Alexander D, Rhymes, Elena R, Gibbs, Katherine L, Greensmith, Linda, Schiavo, Giampietro
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054680/
https://ncbi.nlm.nih.gov/pubmed/32030864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949129
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