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IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons

Signalling endosomes are essential for trafficking of activated ligand–receptor complexes and their distal signalling, ultimately leading to neuronal survival. Although deficits in signalling endosome transport have been linked to neurodegeneration, our understanding of the mechanisms controlling th...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: Fellows, Alexander D, Rhymes, Elena R, Gibbs, Katherine L, Greensmith, Linda, Schiavo, Giampietro
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054680/
https://ncbi.nlm.nih.gov/pubmed/32030864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949129
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