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Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily
The rapid increase of multidrug resistance poses urgent threats to human health. Multidrug transporters prompt multidrug resistance by exporting different therapeutics across cell membranes, often by utilizing the H(+) electrochemical gradient. MdfA from Escherichia coli is a prototypical H(+) -depe...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7054563/ https://ncbi.nlm.nih.gov/pubmed/32127561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60332-8 |
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