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The ROCK isoforms differentially regulate the morphological characteristics of carcinoma cells

Rho-associated kinase (ROCK) activity drives cell migration via actomyosin contractility. During invasion, individual cancer cells can transition between 2 modes of migration, mesenchymal and amoeboid. Changes in ROCK activity can cause a switch between these migration phenotypes which are defined b...

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Detalhes bibliográficos
Publicado no:Small GTPases
Main Authors: Jerrell, Rachel J., Leih, Mitchell J., Parekh, Aron
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053931/
https://ncbi.nlm.nih.gov/pubmed/28650698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2017.1341366
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