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The altered mechanical phenotype of fetal fibroblasts hinders myofibroblast differentiation

During the dermal wound healing process, the mechanical rigidity of the newly deposited extracellular matrix and transforming growth factor‐β1 promote the transition of fibroblasts into myofibroblasts. Myofibroblasts generate large cellular forces that contract and remodel the extracellular matrix l...

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Detalhes bibliográficos
Publicado no:Wound Repair Regen
Main Authors: Jerrell, Rachel J., Leih, Mitchell J., Parekh, Aron
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378408/
https://ncbi.nlm.nih.gov/pubmed/30315715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/wrr.12677
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