A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice

Bile acids (BAs) facilitate intestinal absorption of lipid-soluble nutrients and modulate various metabolic pathways through the farnesoid X receptor (FXR) and Takeda G-protein-coupled receptor 5. These receptors are targets for therapy in cholestatic and metabolic diseases. However, dissimilarities...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: de Boer, Jan Freark, Verkade, Esther, Mulder, Niels L., de Vries, Hilde D., Huijkman, Nicolette, Koehorst, Martijn, Boer, Theo, Wolters, Justina C., Bloks, Vincent W., van de Sluis, Bart, Kuipers, Folkert
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053831/
https://ncbi.nlm.nih.gov/pubmed/31506275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000243
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars