ATM is required for SOD2 Expression and Homeostasis within the Mammary Gland

ATM, the gene mutated in the human disorder Ataxia-Telangiectasia (A-T), is a protein kinase activated in response to genotoxic and oxidative stress. Dysregulated response to redox imbalance is thought to drive many of the pathologies observed in A-T patients. Among the downstream pathways activated...

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Vydáno v:Breast Cancer Res Treat
Hlavní autoři: Dyer, Lisa M., Kepple, Jessica D., Ai, Lingbao, Kim, Wan-Ju, Stanton, Virginia, Reinhard, Mary K., Backman, Lindsey R.F., Streitfeld, W. Scott, Babu, Nivetha Ramesh, Treiber, Nicolai, Scharffetter-Kochanek, Karin, McKinnon, Peter J., Brown, Kevin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053824/
https://ncbi.nlm.nih.gov/pubmed/28849346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4424-0
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