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ATM is required for SOD2 Expression and Homeostasis within the Mammary Gland
ATM, the gene mutated in the human disorder Ataxia-Telangiectasia (A-T), is a protein kinase activated in response to genotoxic and oxidative stress. Dysregulated response to redox imbalance is thought to drive many of the pathologies observed in A-T patients. Among the downstream pathways activated...
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| 發表在: | Breast Cancer Res Treat |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053824/ https://ncbi.nlm.nih.gov/pubmed/28849346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4424-0 |
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