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Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma
PURPOSE: In this study, we constructed novel brain-targeting complexes (U2-AuNP) by conjugating aptamer U2 to the gold nanoparticle (AuNPs) surface as a promising option for GBM therapy. MATERIALS AND METHODS: The properties of the U2-AuNP complexes were thoroughly characterized. Then, we detected t...
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| Publicado en: | Int J Nanomedicine |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053811/ https://ncbi.nlm.nih.gov/pubmed/32184591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S238206 |
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