Aptamer-Conjugated Gold Nanoparticles Targeting Epidermal Growth Factor Receptor Variant III for the Treatment of Glioblastoma

PURPOSE: In this study, we constructed novel brain-targeting complexes (U2-AuNP) by conjugating aptamer U2 to the gold nanoparticle (AuNPs) surface as a promising option for GBM therapy. MATERIALS AND METHODS: The properties of the U2-AuNP complexes were thoroughly characterized. Then, we detected t...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Peng, Li, Liang, Yanling, Zhong, Xinxin, Liang, Zhiman, Tian, Yinghong, Li, Shuji, Liang, Jingxue, Wang, Ransheng, Zhong, Yuqi, Shi, Yusheng, Zhang, Xingmei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053811/
https://ncbi.nlm.nih.gov/pubmed/32184591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S238206
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