Cell-SELEX Aptamer for Highly Specific Radionuclide Molecular Imaging of Glioblastoma In Vivo

Glioblastoma (GBM) is the most frequent and aggressive primary adult brain tumor with poor prognosis. Epidermal growth factor receptor variant III (EGFRvIII) is the most common and highly oncogenic EGFR mutant in GBM. With the aim to generate specific molecular probes able to target EGFRvIII with hi...

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Detalhes bibliográficos
Main Authors: Wu, Xidong, Liang, Huiyu, Tan, Yan, Yuan, Chao, Li, Shuji, Li, Xiaowen, Li, Guiping, Shi, Yusheng, Zhang, Xingmei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948368/
https://ncbi.nlm.nih.gov/pubmed/24603483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090752
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