Carnitine insufficiency is associated with fatigue during lenvatinib treatment in patients with hepatocellular carcinoma

BACKGROUND: Fatigue is a common adverse event during lenvatinib treatment in patients with hepatocellular carcinoma. One mechanism contributing to development of fatigue might involve abnormal adenosine triphosphate synthesis that is caused by carnitine deficiency. To address this possibility, we ex...

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Veröffentlicht in:PLoS One
Hauptverfasser: Okubo, Hironao, Ando, Hitoshi, Ishizuka, Kei, Kitagawa, Ryuta, Okubo, Shoki, Saito, Hiroaki, Kokubu, Shigehiro, Miyazaki, Akihisa, Ikejima, Kenichi, Shiina, Shuichiro, Nagahara, Akihito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053710/
https://ncbi.nlm.nih.gov/pubmed/32126131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229772
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