Plasma concentration and efficacy of tolvaptan in cirrhotic patients with refractory ascites
To investigate the relationship between the exposure and efficacy of tolvaptan, we measured pharmacokinetics of total drug at 7 days after repeated doses of 3.75 mg/day tolvaptan in 16 patients with hepatic edema. Nine patients (56.3%) were responders, which were defined as those with body weight re...
Gardado en:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2019-04-01
|
| Series: | Journal of Pharmacological Sciences |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S1347861319300295 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|