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Pathophysiology of Sickle Cell Disease
Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made in the elucidation of the pathogenesis of its protean complications, which has inspired recent advances in targeted molecular therapies. In SCD, a single amino acid substitution in the β-globin chain leads to p...
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| Publicat a: | Annu Rev Pathol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053558/ https://ncbi.nlm.nih.gov/pubmed/30332562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathmechdis-012418-012838 |
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