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Pathophysiology of Sickle Cell Disease
Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made in the elucidation of the pathogenesis of its protean complications, which has inspired recent advances in targeted molecular therapies. In SCD, a single amino acid substitution in the β-globin chain leads to p...
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| Gepubliceerd in: | Annu Rev Pathol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053558/ https://ncbi.nlm.nih.gov/pubmed/30332562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pathmechdis-012418-012838 |
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