Oxymatrine Liposomes for Intervertebral Disc Treatment: Formulation, in vitro and vivo Assessments

PURPOSE: Intervertebral disc degeneration (IVDD) is the main cause of modern low back pain, leading to high societal economic costs. To find an effective medical treatment for this disease, oxymatrine liposomes (OMT-LIP) were prepared with the pH-gradient method. MATERIALS AND METHODS: Nucleus pulpo...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Wang, Huan, Ding, Yifan, Zhang, Wei, Wei, Kang, Pei, Yaping, Zou, Chenming, Zhang, Chong, Ding, Jiahui, Fang, Huang, Tan, Songwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053530/
https://ncbi.nlm.nih.gov/pubmed/32184561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S242493
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