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Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway

Intervertebral disc degeneration is the main cause of low back pain. However, its pathomechanism has not been fully clarified yet. Previous studies have indicated that inflammation may lead to apoptosis of nucleus pulposus cells and break the balance between anabolism and catabolism of the nucleus p...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Wei, Kang, Dai, Jun, Wang, Zhenggang, Pei, Yaping, Chen, Yan, Ding, Yifan, Ding, Qing, Ahati, Paerxiati, Zhou, Xiaozhong, Wang, Huan, Fang, Huang
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158602/
https://ncbi.nlm.nih.gov/pubmed/31979980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219900773
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