Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway

Intervertebral disc degeneration is the main cause of low back pain. However, its pathomechanism has not been fully clarified yet. Previous studies have indicated that inflammation may lead to apoptosis of nucleus pulposus cells and break the balance between anabolism and catabolism of the nucleus p...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Wei, Kang, Dai, Jun, Wang, Zhenggang, Pei, Yaping, Chen, Yan, Ding, Yifan, Ding, Qing, Ahati, Paerxiati, Zhou, Xiaozhong, Wang, Huan, Fang, Huang
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158602/
https://ncbi.nlm.nih.gov/pubmed/31979980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219900773
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