Berberine prevents human nucleus pulposus cells from IL-1β-induced extracellular matrix degradation and apoptosis by inhibiting the NF-κB pathway

Intervertebral disc degeneration (IDD) is widely considered to be one of the main causes of lower back pain, which is a chronic progressive disease closely related to inflammation, nucleus pulposus (NP) cell apoptosis and extracellular matrix (ECM) degradation. Berberine (BBR) is an alkaloid compoun...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Mol Med
Auteurs principaux: Lu, Lin, Hu, Jialang, Wu, Qipeng, An, Ying, Cui, Wei, Wang, Junwen, Ye, Zhewei
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2019
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414164/
https://ncbi.nlm.nih.gov/pubmed/30816449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2019.4105
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