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Liposomal Oxymatrine in Hepatic Fibrosis Treatment: Formulation, In Vitro and In Vivo Assessment

The aim was to develop a liposomal oxymatrine conjugating d-alpha tocopheryl polyethylene glycol 1000 succinate (OMT-LIP) for enhanced therapeutics of hepatic fibrosis. OMT-LIP was prepared using the remote loading method. The influences of formulation compositions on the encapsulation efficiency of...

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Detalhes bibliográficos
Main Authors: Zhang, Shujuan, Wu, Jun, Wang, Hua, Wang, Tiechuang, Jin, Lina, Shu, Dandan, Shan, Weiguang, Xiong, Subin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037472/
https://ncbi.nlm.nih.gov/pubmed/24515270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0086-y
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