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Methods of Protein Misfolding Cyclic Amplification

Protein misfolding cyclic amplification (PMCA) amplifies infectious prions in vitro. Over the past decade, PMCA has become an essential tool in prion research. The current chapter describes in detail the PMCA format with beads (PMCAb) and several methods that rely on PMCAb for assessing strain-speci...

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Détails bibliographiques
Publié dans:Methods Mol Biol
Auteurs principaux: Makarava, Natallia, Savtchenko, Regina, Baskakov, Ilia V.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052956/
https://ncbi.nlm.nih.gov/pubmed/28861790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7244-9_13
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