Macrovascular Endothelial Cells Enhance the Motility of Liver Cancer Cells by Up-regulation of MMP-3, Activation of Integrin/FAK Signaling Pathway and Induction of Non-classical Epithelial-mesenchymal Transition

Background: Liver cancer with portal vein tumor thrombus (PVTT) indicates a serious prognosis. The molecular mechanism of PVTT formation is not totally clarified, the invasion of blood vessels by liver cancer cells is the key step and portal vein endothelial cells plays critical role. Methods: Condi...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cancer
Auteurs principaux: Ding, Song-Ming, Lu, Ai-Li, Lu, Jian-Fang, Chen, Xu-Liang, Edoo, Muhammad Ibrahim Alhadi, Zhou, Lin, Xie, Hai-Yang, Zheng, Shu-Sen, Li, Qi-Yong
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2020
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052939/
https://ncbi.nlm.nih.gov/pubmed/32127932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.38209
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