Macrovascular Endothelial Cells Enhance the Motility of Liver Cancer Cells by Up-regulation of MMP-3, Activation of Integrin/FAK Signaling Pathway and Induction of Non-classical Epithelial-mesenchymal Transition

Background: Liver cancer with portal vein tumor thrombus (PVTT) indicates a serious prognosis. The molecular mechanism of PVTT formation is not totally clarified, the invasion of blood vessels by liver cancer cells is the key step and portal vein endothelial cells plays critical role. Methods: Condi...

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Udgivet i:J Cancer
Main Authors: Ding, Song-Ming, Lu, Ai-Li, Lu, Jian-Fang, Chen, Xu-Liang, Edoo, Muhammad Ibrahim Alhadi, Zhou, Lin, Xie, Hai-Yang, Zheng, Shu-Sen, Li, Qi-Yong
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052939/
https://ncbi.nlm.nih.gov/pubmed/32127932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.38209
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