FGD1 promotes tumor progression and regulates tumor immune response in osteosarcoma via inhibiting PTEN activity

Rationale: Mesenchymal cell-derived osteosarcoma is a rare malignant bone tumor affecting children and adolescents. PTEN down-regulation or function-loss mutation is associated with the aggressive of osteosarcoma. Explicating the regulatory mechanism of PTEN might highlight new targets for improving...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wu, Wei, Jing, Doudou, Meng, Zibo, Hu, Binwu, Zhong, Binlong, Deng, Xiangyu, Jin, Xin, Shao, Zengwu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052884/
https://ncbi.nlm.nih.gov/pubmed/32194840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41279
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