Icariin Prevents IL-1β-Induced Apoptosis in Human Nucleus Pulposus via the PI3K/AKT Pathway

PURPOSE: To explore the effect and possible mechanism of icariin, a prenylated flavonol glycoside derived from the Chinese herb Epimedium sagittatum that was applied to IL-1β pretreated human nucleus pulposus (NP) cells. METHODS: Human NP cells were isolated from intervertebral discs of patients wit...

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Udgivet i:Evid Based Complement Alternat Med
Main Authors: Deng, Xiangyu, Wu, Wei, Liang, Hang, Huang, Donghua, Jing, Doudou, Zheng, Dong, Shao, Zengwu
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5702406/
https://ncbi.nlm.nih.gov/pubmed/29259641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2198323
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